Here are 3 Bible verses about son leaving mother, curated from both the Old and New Testaments of the Holy Bible, King James Version, arranged from most to least relevant.
Genesis 2:24 KJV
24 Therefore shall a man leave his father and his mother, and shall cleave unto his wife: and they shall be one flesh.
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Ephesians 5:31 KJV
31 For this cause shall a man leave his father and mother, and shall be joined unto his wife, and they two shall be one flesh.
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Matthew 19:5 KJV
5 And said, For this cause shall a man leave father and mother, and shall cleave to his wife: and they twain shall be one flesh?